DETAILED NOTES ON METHADONE

Cost-free and conjugated noroxycodone, cost-free and conjugated oxycodone, and oxymorphone are excreted in human urine subsequent just one oral dose of oxycodone. The foremost circulating metabolite is noroxycodone with the AUC ratio of 0.6 relative to that of oxycodone. Oxymorphone is existing within the plasma only in minimal concentrations. The